Natural killer and lymphokine activated killer cell functions in Hodgkin's disease
نویسندگان
چکیده
منابع مشابه
Lymphokine-Activated Killer Cell Functions in Patients With Leukemic
Nine patients with leukemic B-Iymphoproliferative diseases (B-LPD) were evaluated for development of in vitro recombinant interleukin-2 (rli-2)-activated killer (LAK) cells. B-cell cultures were established from peripheral blood mononuclear cells (PBMNCs) containing 63% ± 29% malignant cells. Short-term cultures were tested after 5-day activation with 500 U rlL-2/mL. long-term cultures were mai...
متن کاملImmunoregulation of natural and lymphokine-activated killer cells by selenium.
The effect of selenium (Se) on natural killer (NK) and lymphokine-activated killer (LAK) cell activities and proliferative responses of human lymphocytes was studied in vitro. Direct addition of Se at 1.0 microgram/ml final concentration to the mixture of target and effector cells during a 4 h cytotoxicity assay significantly suppressed the NK activity of normal lymphocytes. When lymphocytes we...
متن کاملLymphokine-activated killer cells in rats: analysis of progenitor and effector cell phenotype and relationship to natural killer cells.
The progenitor and effector cell phenotype of lymphokine-activated killer (LAK) cells generated in F344 rats by recombinant human interleukin 2 (IL-2) (rIL-2) were analyzed. Highly purified populations of peripheral blood large granular lymphocytes (LGL) exhaustively depleted of T-cells were fully capable of generating high levels of LAK activity by 3 to 5 days in culture while purified populat...
متن کاملLymphokine-activated Killer Cells in Rats: Analysis of Progenitor and Effector Cell Phenotype and Relationship to Natural Killer Cells1
The progenitor and effector cell phenotype of lymphokine-activated killer (LAK) cells generated in 1-344 rats by recombinant human interleukin 2 (IL-2) (rIL-2) were analyzed. Highly purified populations of peripheral blood large granular lymphocytes (LGL) exhaustively de pleted of I -cells were fully capable of generating high levels of LAK activity by 3 to 5 days in culture while purified popu...
متن کاملLymphokine-activated killer-cell traffic in metastatic melanoma.
Data from the population-based registries at Bangalore, Bombay, and Madras indicate paediatric cancer frequencies varying from 37% to 4% 23 In Dibrugarh in north-eastern India and Chandigarh in the north-west the frequency was 2-48%. International comparisons of cancer incidence are potentially fraught by variability in diagnosis, classification, and coding practices, by competing causes of dea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1990
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1990.261